Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CASP1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000834-T02
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CASP1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 35
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CASP1 antibody (H00000834-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000834-T02
    CASP1 transfected lysate.
    Western Blot
    QC Testing of H00000834-T02
    Lane 1: CASP1 transfected lysate ( 35.00 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 834
  • Gene Name:
  • CASP1
  • Gene Alias:
  • ICE,IL1BC,P45
  • Gene Description:
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • CASP1 nirs variant 1,IL1B-convertase,caspase 1,caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase),interleukin 1-B converting enzyme,interleukin 1-beta convertase
  • RSS
  • YouTube
  • Linkedin
  • Facebook