CAPNS1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CAPNS1 partial ORF ( AAH00592, 172 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.42
Interspecies Antigen Sequence
Mouse (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CAPNS1
Entrez GeneID
826GeneBank Accession#
BC000592Protein Accession#
AAH00592Gene Name
CAPNS1
Gene Alias
30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS
Gene Description
calpain, small subunit 1
Omim ID
114170Gene Ontology
HyperlinkGene Summary
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
calcium-activated neutral proteinase|calcium-dependent protease, small subunit|calpain 4, small subunit (30K)|calpain, small polypeptide
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Interactome
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Disease
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