CAPNS1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CAPNS1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CAPNS1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CAPNS1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CAPNS1
Entrez GeneID
826GeneBank Accession#
CAPNS1Gene Name
CAPNS1
Gene Alias
30K, CALPAIN4, CANP, CANPS, CAPN4, CDPS
Gene Description
calpain, small subunit 1
Omim ID
114170Gene Ontology
HyperlinkGene Summary
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
calcium-activated neutral proteinase|calcium-dependent protease, small subunit|calpain 4, small subunit (30K)|calpain, small polypeptide
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Interactome
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