CAMLG 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CAMLG transfected lysate.
Western Blot
Lane 1: CAMLG transfected lysate ( 33 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CAMLG full-length
Host
Human
Theoretical MW (kDa)
33
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CAMLG antibody (H00000819-B01) by Western Blots.
SDS-PAGE Gel
CAMLG transfected lysate.
Western Blot
Lane 1: CAMLG transfected lysate ( 33 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CAMLG
Entrez GeneID
819GeneBank Accession#
NM_001745.2Protein Accession#
-Gene Name
CAMLG
Gene Alias
CAML, MGC163197
Gene Description
calcium modulating ligand
Omim ID
601118Gene Ontology
HyperlinkGene Summary
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq
Other Designations
calcium-modulating cyclophilin ligand|calcium-signal modulating cyclophilin ligand|cyclophilin B-binding protein
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Interactome
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Disease
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