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Last updated: 2016/12/4

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CAMLG Pre-design Chimera RNAi

  • Catalog # : H00000819-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens calcium modulating ligand (CAMLG), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001745
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 819
  • Gene Name:
  • CAMLG
  • Gene Alias:
  • CAML,MGC163197
  • Gene Description:
  • calcium modulating ligand
  • Gene Summary:
  • The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq
  • Other Designations:
  • calcium-modulating cyclophilin ligand,calcium-signal modulating cyclophilin ligand,cyclophilin B-binding protein
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