CAMLG polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
CAMLG polyclonal antibody (A01), Lot # 060717JCS1 Western Blot analysis of CAMLG expression in 293 ( Cat # L026V1 ).
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CAMLG.
Immunogen
CAMLG (NP_001736, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CAMLG polyclonal antibody (A01), Lot # 060717JCS1 Western Blot analysis of CAMLG expression in 293 ( Cat # L026V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — CAMLG
Entrez GeneID
819GeneBank Accession#
NM_001745Protein Accession#
NP_001736Gene Name
CAMLG
Gene Alias
CAML, MGC163197
Gene Description
calcium modulating ligand
Omim ID
601118Gene Ontology
HyperlinkGene Summary
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq
Other Designations
calcium-modulating cyclophilin ligand|calcium-signal modulating cyclophilin ligand|cyclophilin B-binding protein
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Interactome
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Disease
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