SLC25A20 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human SLC25A20 full-length ORF ( AAH01689, 1 a.a. - 301 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MADQPKPISPLKNLLAGGFGGVCLVFAGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPNL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
58.85
Interspecies Antigen Sequence
Mouse (93); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC25A20
Entrez GeneID
788GeneBank Accession#
BC001689Protein Accession#
AAH01689Gene Name
SLC25A20
Gene Alias
CAC, CACT
Gene Description
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
Omim ID
212138Gene Ontology
HyperlinkGene Summary
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq
Other Designations
carnitine/acylcarnitine carrier protein|carnitine/acylcarnitine translocase
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