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CACNB4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000785-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CACNB4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 58.2
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CACNB4 antibody (H00000785-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000785-T01
    CACNB4 transfected lysate.
    Western Blot
    QC Testing of H00000785-T01
    Lane 1: CACNB4 transfected lysate ( 58.2 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 785
  • Protein Accession#:
  • -
  • Gene Name:
  • CACNB4
  • Gene Alias:
  • CAB4,CACNLB4,EA5,EJM
  • Gene Description:
  • calcium channel, voltage-dependent, beta 4 subunit
  • Gene Summary:
  • This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • dihydropyridine-sensitive L-type, calcium channel beta-4 subunit,voltage dependent calcium channel beta 4 subunit
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