CACNB4 monoclonal antibody (M01), clone 7E1
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More Files
- More Functions
Western Blot (Cell lysate)
CACNB4 monoclonal antibody (M01), clone 7E1. Western Blot analysis of CACNB4 expression in K-562.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CACNB4 is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CACNB4.
Immunogen
CACNB4 (NP_000717.2, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDED
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CACNB4 monoclonal antibody (M01), clone 7E1. Western Blot analysis of CACNB4 expression in K-562.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CACNB4 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — CACNB4
Entrez GeneID
785GeneBank Accession#
NM_000726Protein Accession#
NP_000717.2Gene Name
CACNB4
Gene Alias
CAB4, CACNLB4, EA5, EJM
Gene Description
calcium channel, voltage-dependent, beta 4 subunit
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
dihydropyridine-sensitive L-type, calcium channel beta-4 subunit|voltage dependent calcium channel beta 4 subunit
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Interactome
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Pathway
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Disease
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