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DDR1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000780-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DDR1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 96.47
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DDR1 antibody (H00000780-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000780-T01
    DDR1 transfected lysate.
    Western Blot
    QC Testing of H00000780-T01
    Lane 1: DDR1 transfected lysate ( 96.47 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 780
  • Gene Name:
  • DDR1
  • Gene Alias:
  • CAK,CD167,DDR,EDDR1,MCK10,NEP,NTRK4,PTK3,PTK3A,RTK6,TRKE
  • Gene Description:
  • discoidin domain receptor tyrosine kinase 1
  • Gene Summary:
  • Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000029343,OTTHUMP00000029344,OTTHUMP00000029345,OTTHUMP00000029346,OTTHUMP00000029347,PTK3A protein tyrosine kinase 3A,cell adhesion kinase,discoidin domain receptor DDR1d,discoidin domain receptor family, member 1,discoidin receptor tyrosine kin
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