CACNA1S (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CACNA1S partial ORF ( NP_000060, 1743 a.a. - 1838 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
CPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAADANFIMATGQALGDACQMEPEEVEIMATELLKGREA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.3
Interspecies Antigen Sequence
Mouse (61); Rat (57)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CACNA1S
Entrez GeneID
779GeneBank Accession#
NM_000069Protein Accession#
NP_000060Gene Name
CACNA1S
Gene Alias
CACNL1A3, CCHL1A3, Cav1.1, HOKPP, MHS5, hypoPP
Gene Description
calcium channel, voltage-dependent, L type, alpha 1S subunit
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq
Other Designations
OTTHUMP00000033931|calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis)|dihydropyridine receptor|dihydropyridine-sensitive L-type calcium channel alpha-1 subunit|voltage-gated calcium channel subunit al
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Interactome
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Pathway
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Disease
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