CACNA1S monoclonal antibody (M01), clone 2C5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CACNA1S.
Immunogen
CACNA1S (NP_000060, 1743 a.a. ~ 1838 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
CPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAADANFIMATGQALGDACQMEPEEVEIMATELLKGREA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (61); Rat (57)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CACNA1S is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — CACNA1S
Entrez GeneID
779GeneBank Accession#
NM_000069Protein Accession#
NP_000060Gene Name
CACNA1S
Gene Alias
CACNL1A3, CCHL1A3, Cav1.1, HOKPP, MHS5, hypoPP
Gene Description
calcium channel, voltage-dependent, L type, alpha 1S subunit
Gene Ontology
HyperlinkGene Summary
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq
Other Designations
OTTHUMP00000033931|calcium channel, L type, alpha 1 polypeptide, isoform 3 (skeletal muscle, hypokalemic periodic paralysis)|dihydropyridine receptor|dihydropyridine-sensitive L-type calcium channel alpha-1 subunit|voltage-gated calcium channel subunit al
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Interactome
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Pathway
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Disease
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