Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

CACNA1E

Gene Alias

BII, CACH6, CACNL1A6, Cav2.3

Gene Description

calcium channel, voltage-dependent, R type, alpha 1E subunit

Omim ID

Gene Ontology

Gene Summary

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants of the gene described here have been observed but have not been thoroughly characterized. [provided by RefSeq

Other Designations

OTTHUMP00000042484|OTTHUMP00000042485|OTTHUMP00000042486|brain calcium channel II|calcium channel, R type, alpha-1 polypeptide, isoform 6|calcium channel, voltage-dependent, alpha 1E subunit|voltage-dependent calcium channel alpha 1E subunit|voltage-gated