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Last updated: 2016/12/11
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CACNA1C monoclonal antibody (M20), clone 4D10

  • Catalog # : H00000775-M20
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant CACNA1C.
  • Immunogen:
  • CACNA1C (NP_000710, 2039 a.a. ~ 2138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • AVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG1 Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00000775-M20
    Western Blot detection against Immunogen (36.74 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged CACNA1C is 0.03 ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 775
  • Gene Name:
  • CACNA1C
  • Gene Alias:
  • CACH2,CACN2,CACNL1A1,CCHL1A1,CaV1.2,MGC120730,TS
  • Gene Description:
  • calcium channel, voltage-dependent, L type, alpha 1C subunit
  • Gene Summary:
  • This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq
  • Other Designations:
  • DHPR, alpha-1 subunit,calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle,calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit,voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*,voltage-gated c
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