CA8 monoclonal antibody (M01), clone 1F7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CA8.
Immunogen
CA8 (NP_004047, 40 a.a. ~ 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPME
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG3 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CA8 monoclonal antibody (M01), clone 1F7 Western Blot analysis of CA8 expression in A-549 ( Cat # L025V1 ).Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CA8 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — CA8
Entrez GeneID
767GeneBank Accession#
NM_004056Protein Accession#
NP_004047Gene Name
CA8
Gene Alias
CA-VIII, CALS, CARP, MGC120502, MGC99509
Gene Description
carbonic anhydrase VIII
Omim ID
114815Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq
Other Designations
CA-related protein|carbonate dehydratase|carbonic anhydrase-like sequence|carbonic anhydrase-related protein
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Interactome
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Pathway
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Disease
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