CA4 DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human CA4 DNA using DNAx™ Immune technology.
Technology
Immunogen
CA4 (NP_000708.1, 19 a.a. ~ 284 a.a) partial-length human DNA
Sequence
AESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CA4 expression in transfected 293T cell line by CA4 DNAxPab polyclonal antibody.
Lane 1: CA4 transfected lysate(50.38 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CA4
Entrez GeneID
762GeneBank Accession#
NM_000717.2Protein Accession#
NP_000708.1Gene Name
CA4
Gene Alias
CAIV, Car4, RP17
Gene Description
carbonic anhydrase IV
Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq
Other Designations
carbonic dehydratase|retinitis pigmentosa 17 (autosomal dominant)
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Interactome
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Pathway
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Disease
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