CA4 monoclonal antibody (M08), clone 4G6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CA4.
Immunogen
CA4 (NP_000708.1, 27 a.a. ~ 126 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (51); Rat (52)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CA4 monoclonal antibody (M08), clone 4G6. Western Blot analysis of CA4 expression in A-431.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CA4 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — CA4
Entrez GeneID
762GeneBank Accession#
NM_000717Protein Accession#
NP_000708.1Gene Name
CA4
Gene Alias
CAIV, Car4, RP17
Gene Description
carbonic anhydrase IV
Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq
Other Designations
carbonic dehydratase|retinitis pigmentosa 17 (autosomal dominant)
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Interactome
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Disease
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