CA2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CA2 full-length ORF ( NP_000058.1, 1 a.a. - 260 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
55.6
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CA2
Entrez GeneID
760GeneBank Accession#
NM_000067.1Protein Accession#
NP_000058.1Gene Name
CA2
Gene Alias
CA-II, CAII, Car2
Gene Description
carbonic anhydrase II
Gene Ontology
HyperlinkGene Summary
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. [provided by RefSeq
Other Designations
carbonate dehydratase II|carbonic anhydrase B|carbonic dehydratase
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Interactome
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Pathway
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Disease
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Publication Reference
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Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease.
Buelli S, Perico L, Galbusera M, Abbate M, Morigi M, Novelli R, Gagliardini E, Tentori C, Rottoli D, Sabadini E, Saito T, Kawano M, Saeki T, Zoja C, Remuzzi G, Benigni A.
EBioMedicine 2015 Mar; 2(5):456.
Application:WB, Human, Serum.
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Mitochondrial-dependent Autoimmunity in Membranous Nephropathy of IgG4-related Disease.
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