CA1 monoclonal antibody (M19), clone 10E4
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More Files
- More Functions
Western Blot (Tissue lysate)
CA1 monoclonal antibody (M19), clone 10E4. Western Blot analysis of CA1 expression in human lung cancer.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CA1 is approximately 0.3ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CA1.
Immunogen
CA1 (AAH27890, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (81)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CA1 monoclonal antibody (M19), clone 10E4. Western Blot analysis of CA1 expression in human lung cancer.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CA1 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — CA1
Entrez GeneID
759GeneBank Accession#
BC027890Protein Accession#
AAH27890Gene Name
CA1
Gene Alias
Car1
Gene Description
carbonic anhydrase I
Omim ID
114800Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq
Other Designations
carbonic dehydratase
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Interactome
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Pathway
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Disease
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