C4BPB 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
C4BPB transfected lysate.
Western Blot
Lane 1: C4BPB transfected lysate ( 27.83 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-C4BPB full-length
Host
Human
Theoretical MW (kDa)
27.83
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-C4BPB antibody (H00000725-B01) by Western Blots.
SDS-PAGE Gel
C4BPB transfected lysate.
Western Blot
Lane 1: C4BPB transfected lysate ( 27.83 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — C4BPB
Entrez GeneID
725GeneBank Accession#
NM_001017367.1Protein Accession#
NP_001017367.1Gene Name
C4BPB
Gene Alias
C4BP
Gene Description
complement component 4 binding protein, beta
Omim ID
120831Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq
Other Designations
C4b binding protein, beta chain|OTTHUMP00000034288|OTTHUMP00000034289|OTTHUMP00000034375|complement component 4 binding protein, beta chain|complement component 4-binding protein, beta
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Interactome
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Pathway
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Disease
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