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C4BPB Pre-design Chimera RNAi

  • Catalog # : H00000725-R03
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  • Specification
  • Product Description:
  • Homo sapiens complement component 4 binding protein, beta (C4BPB), transcript variant 3, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001017365
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 725
  • Gene Name:
  • C4BPB
  • Gene Alias:
  • C4BP
  • Gene Description:
  • complement component 4 binding protein, beta
  • Gene Summary:
  • This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • C4b binding protein, beta chain,OTTHUMP00000034288,OTTHUMP00000034289,OTTHUMP00000034375,complement component 4 binding protein, beta chain,complement component 4-binding protein, beta
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