C4BPB (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of C4BPB transfected lysate using mouse monoclonal anti-C4BPB and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-C4BPB.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of C4BPB transfected lysate using mouse monoclonal anti-C4BPB and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-C4BPB.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-C4BPB (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-C4BPB (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — C4BPB
Entrez GeneID
725Gene Name
C4BPB
Gene Alias
C4BP
Gene Description
complement component 4 binding protein, beta
Omim ID
120831Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq
Other Designations
C4b binding protein, beta chain|OTTHUMP00000034288|OTTHUMP00000034289|OTTHUMP00000034375|complement component 4 binding protein, beta chain|complement component 4-binding protein, beta
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Interactome
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Pathway
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Disease
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