C4BPB MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of C4BPB expression in transfected 293T cell line (H00000725-T01) by C4BPB MaxPab polyclonal antibody.
Lane 1: C4BPB transfected lysate(28.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of C4BPB transfected lysate using anti-C4BPB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with C4BPB purified MaxPab mouse polyclonal antibody (B01P) (H00000725-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human C4BPB protein.
Immunogen
C4BPB (NP_001017367.1, 1 a.a. ~ 252 a.a) full-length human protein.
Sequence
MFFWCACCLMVAWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of C4BPB expression in transfected 293T cell line (H00000725-T01) by C4BPB MaxPab polyclonal antibody.
Lane 1: C4BPB transfected lysate(28.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of C4BPB transfected lysate using anti-C4BPB MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with C4BPB purified MaxPab mouse polyclonal antibody (B01P) (H00000725-B01P). -
Gene Info — C4BPB
Entrez GeneID
725GeneBank Accession#
NM_001017367.1Protein Accession#
NP_001017367.1Gene Name
C4BPB
Gene Alias
C4BP
Gene Description
complement component 4 binding protein, beta
Omim ID
120831Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq
Other Designations
C4b binding protein, beta chain|OTTHUMP00000034288|OTTHUMP00000034289|OTTHUMP00000034375|complement component 4 binding protein, beta chain|complement component 4-binding protein, beta
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Interactome
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Pathway
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Disease
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