C4BPB (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human C4BPB.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00000725-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 3 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-C4BPB (100 ug)
2. Detection antibody: mouse monoclonal anti-C4BPB, IgG2a Kappa (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — C4BPB
Entrez GeneID
725Gene Name
C4BPB
Gene Alias
C4BP
Gene Description
complement component 4 binding protein, beta
Omim ID
120831Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq
Other Designations
C4b binding protein, beta chain|OTTHUMP00000034288|OTTHUMP00000034289|OTTHUMP00000034375|complement component 4 binding protein, beta chain|complement component 4-binding protein, beta
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