C4BPA 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-C4BPA full-length
Host
Human
Theoretical MW (kDa)
65.78
Interspecies Antigen Sequence
Rat (59)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-C4BPA antibody (H00000722-B01) by Western Blots.
SDS-PAGE Gel
C4BPA transfected lysate.
Western Blot
Lane 1: C4BPA transfected lysate ( 65.78 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — C4BPA
Entrez GeneID
722GeneBank Accession#
NM_000715.3Protein Accession#
NP_000706.1Gene Name
C4BPA
Gene Alias
C4BP, PRP
Gene Description
complement component 4 binding protein, alpha
Omim ID
120830Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq
Other Designations
C4b binding protein, alpha chain|OTTHUMP00000034376|complement component 4 binding protein, alpha chain|complement component 4-binding protein, alpha|proline-rich protein
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Interactome
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Pathway
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Disease
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