SERPING1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SERPING1 full-length
Host
Human
Theoretical MW (kDa)
55.2
Interspecies Antigen Sequence
Mouse (69); Rat (67)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SERPING1 antibody (H00000710-B01) by Western Blots.
SDS-PAGE Gel
SERPING1 transfected lysate.
Western Blot
Lane 1: SERPING1 transfected lysate ( 55.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SERPING1
Entrez GeneID
710GeneBank Accession#
BC011171.2Protein Accession#
-Gene Name
SERPING1
Gene Alias
C1IN, C1INH, C1NH, HAE1, HAE2
Gene Description
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq
Other Designations
complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1
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Interactome
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Pathway
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Disease
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