SERPING1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SERPING1 full-length ORF ( AAH11171, 1 a.a. - 500 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFMLWDQQHKFPVFMGRVYDPRA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
80.52
Interspecies Antigen Sequence
Mouse (69); Rat (67)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SERPING1
Entrez GeneID
710GeneBank Accession#
BC011171Protein Accession#
AAH11171Gene Name
SERPING1
Gene Alias
C1IN, C1INH, C1NH, HAE1, HAE2
Gene Description
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq
Other Designations
complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1
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Interactome
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Pathway
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Disease
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