SERPING1 monoclonal antibody (M01), clone 3F4-1D9
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More Files
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Western Blot (Tissue lysate)
SERPING1 monoclonal antibody (M01), clone 3F4-1D9. Western Blot analysis of SERPING1 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of SERPING1 expression in transfected 293T cell line by SERPING1 monoclonal antibody (M01), clone 3F4-1D9.
Lane 1: SERPING1 transfected lysate (Predicted MW: 55.2 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SERPING1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1 ug/ml]
Immunoprecipitation
Immunoprecipitation of SERPING1 transfected lysate using anti-SERPING1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SERPING1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SERPING1 is approximately 0.1ng/ml as a capture antibody.
Western Blot detection against Immunogen (80.52 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant SERPING1.
Immunogen
SERPING1 (AAH11171, 1 a.a. ~ 500 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFMLWDQQHKFPVFMGRVYDPRA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (67)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (80.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SERPING1 monoclonal antibody (M01), clone 3F4-1D9. Western Blot analysis of SERPING1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of SERPING1 expression in transfected 293T cell line by SERPING1 monoclonal antibody (M01), clone 3F4-1D9.
Lane 1: SERPING1 transfected lysate (Predicted MW: 55.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to SERPING1 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 1 ug/ml]Immunoprecipitation
Immunoprecipitation of SERPING1 transfected lysate using anti-SERPING1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SERPING1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SERPING1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — SERPING1
Entrez GeneID
710GeneBank Accession#
BC011171Protein Accession#
AAH11171Gene Name
SERPING1
Gene Alias
C1IN, C1INH, C1NH, HAE1, HAE2
Gene Description
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq
Other Designations
complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1
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Interactome
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Pathway
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Disease
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