BST2 purified MaxPab mouse polyclonal antibody (B03P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human BST2 protein.
Immunogen
BST2 (AAH33873, 40 a.a. ~ 180 a.a) full-length human protein.
Sequence
PLIIFTIKANSEACRDGLRAVMECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEITTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSSAAAPQLLIVLLGLSALLQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BST2 MaxPab polyclonal antibody. Western Blot analysis of BST2 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of BST2 expression in transfected 293T cell line (H00000684-T05) by BST2 MaxPab polyclonal antibody.
Lane 1: BST2 transfected lysate(19.91 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BST2
Entrez GeneID
684GeneBank Accession#
BC033873Protein Accession#
AAH33873Gene Name
BST2
Gene Alias
CD317
Gene Description
bone marrow stromal cell antigen 2
Omim ID
600534Gene Ontology
HyperlinkGene Summary
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq
Other Designations
tetherin
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Interactome
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Disease
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Publication Reference
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Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence.
Polyak MJ, Vivithanaporn P, Maingat FG, Walsh JG, Branton W, Cohen EA, Meeker R, Power C.
FASEB Journal 2013 Jul; 27(7):2829.
Application:WB-Tr, Mouse, BHK-21 cells.
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HIV-1 Vpu Antagonizes BST-2 by Interfering Mainly with the Trafficking of Newly Synthesized BST-2 to the Cell Surface.
Mathieu Dube, Catherine Paquay, Bibhuti Bhusan Roy, Mariana G Bego, Johanne Mercier, Eric A Cohen.
Traffic (Copenhagen, Denmark) 2011 Dec; 12(12):1714.
Application:Flow Cyt, IF, Human, HeLa, Jurkat cells.
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Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue.
Schindler M, Rajan D, Banning C, Wimmer P, Koppensteiner H, Iwanski A, Specht A, Sauter D, Dobner T, Kirchhoff F.
Retrovirology 2010 Jan; 7:1.
Application:WB-Tr, Human, 293T cells.
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Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence.
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