CEACAM1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CEACAM1 full-length
Host
Human
Theoretical MW (kDa)
51.15
Interspecies Antigen Sequence
Mouse (54); Rat (55)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CEACAM1 antibody (H00000634-B01) by Western Blots.
SDS-PAGE Gel
CEACAM1 transfected lysate.
Western Blot
Lane 1: CEACAM1 transfected lysate ( 51.15 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CEACAM1
Entrez GeneID
634GeneBank Accession#
NM_001024912.1Protein Accession#
NP_001020083.1Gene Name
CEACAM1
Gene Alias
BGP, BGP1, BGPI
Gene Description
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Omim ID
109770Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. [provided by RefSeq
Other Designations
CD66a antigen|antigen CD66|biliary glycoprotein adhesion molecule|carcinoembryonic antigen-related cell adhesion molecule 1
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Interactome
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