BDKRB2 monoclonal antibody (M01), clone 3F6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BDKRB2.
Immunogen
BDKRB2 (NP_000614, 1 a.a. ~ 60 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (53); Rat (48)
Isotype
IgG1 lambda
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.34 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BDKRB2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — BDKRB2
Entrez GeneID
624GeneBank Accession#
NM_000623Protein Accession#
NP_000614Gene Name
BDKRB2
Gene Alias
B2R, BK-2, BK2, BKR2, BRB2, DKFZp686O088
Gene Description
bradykinin receptor B2
Omim ID
113503Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes.
Gu J, Al-Bayati K, Ho EA.
Drug Delivery and Translational Research 2017 Mar; [Epub].
Application:Flow Cyt, Func, Human, hCMEC/D3, U138-MG cells.
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Development of antibody-modified chitosan nanoparticles for the targeted delivery of siRNA across the blood-brain barrier as a strategy for inhibiting HIV replication in astrocytes.
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