BDKRB1 monoclonal antibody (M04), clone 3A2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant BDKRB1.
Immunogen
BDKRB1 (AAH34705, 1 a.a. ~ 353 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BDKRB1 monoclonal antibody (M04), clone 3A2. Western Blot analysis of BDKRB1 expression in human liver.Western Blot (Cell lysate)
BDKRB1 monoclonal antibody (M04), clone 3A2. Western Blot analysis of BDKRB1 expression in MCF-7.ELISA
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Gene Info — BDKRB1
Entrez GeneID
623GeneBank Accession#
BC034705Protein Accession#
AAH34705Gene Name
BDKRB1
Gene Alias
B1BKR, B1R, BKB1R, BKR1, BRADYB1
Gene Description
bradykinin receptor B1
Omim ID
600337Gene Ontology
HyperlinkGene Summary
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq
Other Designations
BK-1 receptor|bradykinin B1 receptor|bradykinin receptor 1
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Interactome
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Pathway
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Disease
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