BDH1 monoclonal antibody (M03), clone 4B3
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant BDH1.
Immunogen
BDH1 (AAH11964, 1 a.a. ~ 343 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (63.47 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
BDH1 monoclonal antibody (M03), clone 4B3. Western Blot analysis of BDH1 expression in NIH/3T3(Cat # L018V1 ).Western Blot (Cell lysate)
BDH1 monoclonal antibody (M03), clone 4B3. Western Blot analysis of BDH1 expression in Raw 264.7 ( Cat # L024V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — BDH1
Entrez GeneID
622GeneBank Accession#
BC011964Protein Accession#
AAH11964Gene Name
BDH1
Gene Alias
BDH, MGC2723, MGC4347, MGC9788, SDR9C1
Gene Description
3-hydroxybutyrate dehydrogenase, type 1
Omim ID
603063Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
(R)-3-hydroxybutyrate dehydrogenase|3-hydroxybutyrate dehydrogenase|3-hydroxybutyrate dehydrogenase (heart, mitochondrial)|D-beta-hydroxybutyrate dehydrogenase, mitochondrial|short chain dehydrogenase/reductase family 9C, member 1
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Interactome
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Pathway
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