BCS1L (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human BCS1L partial ORF ( NP_004319, 320 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLRATNQISPAQVQGYFMLYKNDPVGAIHNAESLR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BCS1L
Entrez GeneID
617GeneBank Accession#
NM_004328Protein Accession#
NP_004319Gene Name
BCS1L
Gene Alias
BCS, BCS1, BJS, FLNMS, GRACILE, Hs.6719, PTD, h-BCS
Gene Description
BCS1-like (yeast)
Gene Ontology
HyperlinkGene Summary
This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Two alternatively spliced transcripts encoding the same protein have been described. [provided by RefSeq
Other Designations
BCS1-like|BCS1-like protein|OTTHUMP00000164147|mitochondrial chaperone BCS1|mitochondrial complex III assembly
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