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BCR 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000613-T02
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BCR full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 121
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BCR antibody (H00000613-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000613-T02
    BCR transfected lysate.
    Western Blot
    QC Testing of H00000613-T02
    Lane 1: BCR transfected lysate ( 121.00 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 613
  • Gene Name:
  • BCR
  • Gene Alias:
  • ALL,BCR-ABL1,BCR1,CML,D22S11,D22S662,FLJ16453,PHL
  • Gene Description:
  • breakpoint cluster region
  • Gene Summary:
  • A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • bcr-abl1 e14a3 chimeric protein
  • Interactome
  • Interactome
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