BCL2L2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human BCL2L2 full-length ORF ( NP_004041.1, 1 a.a. - 193 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.86
Interspecies Antigen Sequence
Mouse (99); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BCL2L2
Entrez GeneID
599GeneBank Accession#
NM_004050.2Protein Accession#
NP_004041.1Gene Name
BCL2L2
Gene Alias
BCL-W, BCLW, KIAA0271
Gene Description
BCL2-like 2
Omim ID
601931Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. [provided by RefSeq
Other Designations
BCL2-like 2 protein|apoptosis regulator BCL-W
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Interactome
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Disease
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