BCL2L2 monoclonal antibody (M01), clone 2E4
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant BCL2L2.
Immunogen
BCL2L2 (NP_004041.1, 1 a.a. ~ 193 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BCL2L2 monoclonal antibody (M01), clone 2E4. Western Blot analysis of BCL2L2 expression in human colon.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BCL2L2 is 10 ng/ml as a capture antibody.ELISA
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Gene Info — BCL2L2
Entrez GeneID
599GeneBank Accession#
NM_004050.2Protein Accession#
NP_004041.1Gene Name
BCL2L2
Gene Alias
BCL-W, BCLW, KIAA0271
Gene Description
BCL2-like 2
Omim ID
601931Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. [provided by RefSeq
Other Designations
BCL2-like 2 protein|apoptosis regulator BCL-W
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Interactome
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Disease
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