BCAT1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human BCAT1 full-length ORF ( AAH33864, 1 a.a. - 320 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWDTELSLFSINLPDFLQFIYF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.94
Interspecies Antigen Sequence
Mouse (84); Rat (74)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — BCAT1
Entrez GeneID
586GeneBank Accession#
BC033864Protein Accession#
AAH33864Gene Name
BCAT1
Gene Alias
BCT1, DKFZp686E12175, ECA39, MECA39, PNAS-121, PP18
Gene Description
branched chain aminotransferase 1, cytosolic
Omim ID
113520Gene Ontology
HyperlinkGene Summary
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. [provided by RefSeq
Other Designations
branched-chain-amino-acid aminotransferase, cytosolic|placental protein 18
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Interactome
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Pathway
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Disease
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