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BBS4 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000585-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BBS4 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 57.2
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BBS4 antibody (H00000585-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000585-T01
    BBS4 transfected lysate.
    Western Blot
    QC Testing of H00000585-T01
    Lane 1: BBS4 transfected lysate ( 57.2 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 585
  • Protein Accession#:
  • -
  • Gene Name:
  • BBS4
  • Gene Alias:
  • -
  • Gene Description:
  • Bardet-Biedl syndrome 4
  • Gene Summary:
  • This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified
  • Other Designations:
  • -
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