BAK1 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of BAK1 transfected lysate using mouse monoclonal anti-BAK1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-BAK1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of BAK1 transfected lysate using mouse monoclonal anti-BAK1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-BAK1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-BAK1 (300 ul)
2. Antibody pair for WB: rabbit polyclonal anti-BAK1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — BAK1
Entrez GeneID
578Gene Name
BAK1
Gene Alias
BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Gene Description
BCL2-antagonist/killer 1
Omim ID
600516Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq
Other Designations
BCL2-like 7 protein|Bcl-2 homologous antagonist/killer|OTTHUMP00000016211|OTTHUMP00000039620|apoptosis regulator BAK|pro-apoptotic protein BAK
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Interactome
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Disease
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