ATP4B rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ATP4B peptide using ARM Technology.
Immunogen
A synthetic peptide of human ATP4B is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ATP4B peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ATP4B
Entrez GeneID
496GeneBank Accession#
ATP4BGene Name
ATP4B
Gene Alias
ATP6B
Gene Description
ATPase, H+/K+ exchanging, beta polypeptide
Omim ID
137217Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq
Other Designations
ATPase, H+/K+ transporting, beta polypeptide|gastric H+/K+ ATPase beta subunit|gastric hydrogen-potassium ATPase, beta|hydrogen/potassium-exchanging ATPase 4B|potassium-transporting ATPase beta chain|proton pump beta chain
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