ATP2B4 monoclonal antibody (M03A), clone 2C7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ATP2B4.
Immunogen
ATP2B4 (NP_001675, 1 a.a. ~ 92 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKT
Host
Mouse
Reactivity
Human
Isotype
IgG IgA IgM Mix Lambda
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.86 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ATP2B4
Entrez GeneID
493GeneBank Accession#
NM_001684Protein Accession#
NP_001675Gene Name
ATP2B4
Gene Alias
ATP2B2, DKFZp686G08106, DKFZp686M088, MXRA1, PMCA4, PMCA4b, PMCA4x
Gene Description
ATPase, Ca++ transporting, plasma membrane 4
Omim ID
108732Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000034088|OTTHUMP00000034089|matrix-remodelling associated 1|plasma membrane calcium ATPase 4|plasma membrane calcium pump|sarcolemmal calcium pump
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