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ATP2A2 rabbit monoclonal antibody

  • Catalog # : H00000488-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ATP2A2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ATP2A2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ATP2A2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 488
  • Gene Name:
  • ATP2A2
  • Gene Alias:
  • ATP2B,DAR,DD,DKFZp686P0211,FLJ20293,FLJ38063,MGC45367,SERCA2
  • Gene Description:
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • Gene Summary:
  • This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2,ATPase, Ca++ transporting, slow twitch 2,SR Ca(2+)-ATPase 2,calcium pump 2,calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform,cardiac Ca2+ ATPase,endoplasmic r
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