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SERPINC1 (Human) Recombinant Protein (P01)

  • Catalog # : H00000462-P01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human SERPINC1 full-length ORF ( AAH22309.1, 1 a.a. - 259 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 54.23
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00000462-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 462
  • Gene Name:
  • SERPINC1
  • Gene Alias:
  • AT3,ATIII,MGC22579
  • Gene Description:
  • serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Gene Summary:
  • The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035393,antithrombin (aa 375-432),antithrombin III,coding sequence signal peptide antithrombin part 1,serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1,signal peptide antithrombin part 1
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