ASS1 monoclonal antibody (M02), clone 2D2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ASS1.
Immunogen
ASS1 (NP_000041.2, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ASS1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ASS1
Entrez GeneID
445GeneBank Accession#
NM_000050Protein Accession#
NP_000041.2Gene Name
ASS1
Gene Alias
ASS, CTLN1
Gene Description
argininosuccinate synthetase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022362|OTTHUMP00000022363|OTTHUMP00000022364|citrulline--aspartate ligase
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Interactome
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Pathway
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Disease
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