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Last updated: 2016/12/4

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ASL Pre-design Chimera RNAi

  • Catalog # : H00000435-R04
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens argininosuccinate lyase (ASL), transcript variant 4, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001024946
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 435
  • Gene Name:
  • ASL
  • Gene Alias:
  • ASAL
  • Gene Description:
  • argininosuccinate lyase
  • Gene Summary:
  • This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024494,OTTHUMP00000159903,argininosuccinase
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