ASGR1 monoclonal antibody (M03), clone 1G4
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Specification
Product Description
Mouse monoclonal antibody raised against human ASGR1.
Immunogen
A synthetic peptide corresponding to human ASGR1
Sequence
GRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGC
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ASGR1 monoclonal antibody (M03), clone 1G4. Western Blot analysis of ASGR1 expression in human liver.Western Blot (Cell lysate)
ASGR1 monoclonal antibody (M03), clone 1G4. Western Blot analysis of ASGR1 expression in HepG2.ELISA
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Gene Info — ASGR1
Entrez GeneID
432GeneBank Accession#
NM_001671.4Protein Accession#
NP_001662.1Gene Name
ASGR1
Gene Alias
HL-1, ASGPR, ASGPR1, CLEC4H1
Gene Description
asialoglycoprotein receptor 1
Omim ID
108360Gene Ontology
HyperlinkGene Summary
Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. [provided by RefSeq
Other Designations
C-type lectin domain family 4, member H1|hepatic lectin H1
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