ASCL1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ASCL1 expression in transfected 293T cell line by ASCL1 polyclonal antibody (A01).
Lane1:ASCL1 transfected lysate (Predicted MW: 25.5 KDa).
Lane2:Non-transfected lysate.
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ASCL1.
Immunogen
ASCL1 (NP_004307, 137 a.a. ~ 236 a.a) partial recombinant protein with GST tag.
Sequence
GFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ASCL1 expression in transfected 293T cell line by ASCL1 polyclonal antibody (A01).
Lane1:ASCL1 transfected lysate (Predicted MW: 25.5 KDa).
Lane2:Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — ASCL1
Entrez GeneID
429GeneBank Accession#
NM_004316Protein Accession#
NP_004307Gene Name
ASCL1
Gene Alias
ASH1, HASH1, MASH1, bHLHa46
Gene Description
achaete-scute complex homolog 1 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq
Other Designations
achaete scute protein|achaete-scute complex homolog 1|achaete-scute complex-like 1
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Interactome
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Disease
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