ARRB2 monoclonal antibody (M06J), clone 4D2
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More Files
- More Functions
Western Blot (Cell lysate)
ARRB2 monoclonal antibody (M06J), clone 4D2. Western Blot analysis of ARRB2 expression in HepG2.
Western Blot (Cell lysate)
ARRB2 monoclonal antibody (M06J), clone 4D2. Western Blot analysis of ARRB2 expression in PC-12.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ARRB2 is 0.3 ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to ARRB2 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ARRB2.
This product is belong to Cell Culture Grade Antibody (CX Grade).Immunogen
ARRB2 (AAH07427.1, 300 a.a. ~ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC
Host
Mouse
Reactivity
Human, Rat
Preparation Method
Cell Culture Production
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ARRB2 monoclonal antibody (M06J), clone 4D2. Western Blot analysis of ARRB2 expression in HepG2.Western Blot (Cell lysate)
ARRB2 monoclonal antibody (M06J), clone 4D2. Western Blot analysis of ARRB2 expression in PC-12.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ARRB2 is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to ARRB2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — ARRB2
Entrez GeneID
409GeneBank Accession#
BC007427.2Protein Accession#
AAH07427.1Gene Name
ARRB2
Gene Alias
ARB2, ARR2, BARR2, DKFZp686L0365
Gene Description
arrestin, beta 2
Omim ID
107941Gene Ontology
HyperlinkGene Summary
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq
Other Designations
arrestin 3
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Interactome
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Pathway
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Disease
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