ARNTL rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ARNTL peptide using ARM Technology.
Immunogen
A synthetic peptide of human ARNTL is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ARNTL peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ARNTL
Entrez GeneID
406GeneBank Accession#
ARNTLGene Name
ARNTL
Gene Alias
BMAL1, BMAL1c, JAP3, MGC47515, MOP3, PASD3, TIC, bHLHe5
Gene Description
aryl hydrocarbon receptor nuclear translocator-like
Omim ID
602550Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ARNT-like protein 1, brain and muscle|bHLH-PAS protein JAP3|basic-helix-loop-helix-PAS orphan MOP3|member of PAS superfamily 3
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Interactome
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Disease
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